A biological clock - Aging Research at the cellular level 'age in detail, Biology trundle build Oldetopia
A large part of aging research address aging at the cellular level. It examines, among other things if there is a relationship between cell division and aging. The research trundle build is conducted in the laboratory, taking advantage of you, that cells are like tiny organisms that can multiply if given the right medium to grow in. It is, for example, skin cells from people very well suited for. By looking closely at cell division has been observed several notable trundle build conditions that have to do with the aging process. Hayflickgrænsen
In 1961, researchers conducted Leonard Hayflick and Moorhead Paul a series of experiments showed that cells grown in the laboratory only can divide a limited number of times. The cells in which it goes into a state in which they do not share more. This limit cell division was called the Hayflick limit.
Hayflick worked with the type of cells, called fibroblasts, which is the body's connective tissue. trundle build Fibroblasts can be extracted from a skin sample are then put in a shallow bowl with a growth medium. The cells will then divide until they cover the entire bowl area in a single layer. If you put some of these new cells into another bowl with growth medium, these cells also multiply until they cover the whole new dish. Hayflick observed that younger human fibroblasts could divide approx. 50 times and no longer.
Hayflick had also observed that while cells from children to share up to 60 times, then, cells from older people only divide about. 20 times. trundle build Based on this observation made Hayflick the hypothesis that this sharing mechanism was fundamental to aging and death.
Hayflicks theories have in recent years been expanded, trundle build inter alia theory telomerforkortelse for each cell division. The cell's genetic material consisting of 23 chromosome pairs containing the genes. The molecular biologists have discovered that chromosome ends are protected by a special structure, called telomeres. When a person fertilization telomeres their maximum length. Each time the cell divides, the telomeres become shorter. The older a person is, the shorter the individual trundle build cell's telomeres. Finally, the telomers are no longer able to protect the chromosomes, and the cell dies. Telomere theory trundle build thus explains why our cells age and eventually will not divide anymore.
The enzyme telomerase can lengthen telomeres, and it might be tempting to imagine that one could prevent cell death by adding the enzyme. Such cells are available, however. Cancer cells contain trundle build telomerase, and is principally characterized by being immortal. So even telomeraseenzymet can prevent cell aging and death, it may not be in the organism of interest.
Telomere theory can not explain why there is so much variation in human life, as we all start life with the same length trundle build telomeres. Therefore, researchers consider other explanatory models must complement trundle build telomere theory. Some researchers argue against the uncritical transfer theories from laboratory petri dishes in which the cells are grown in culture to the entire organism. They have, among other things discovered that cells in certain tissues splits up to 1000 times without problems, and other studies indicate telomerase in tissues in need of cell renewal. Another objection to the telomere theory as an explanation for why we age, is that the telomeres in older people is so long that the basis of telomere theory should have a life expectancy that is 25-50 years of what it is day.
Articles and Themes Biology age in minute detail the aging population, the aging body History Old age in medicine history Aging in mentality story The dream of eternal trundle build life Oldetopia press Releases
A large part of aging research address aging at the cellular level. It examines, among other things if there is a relationship between cell division and aging. The research trundle build is conducted in the laboratory, taking advantage of you, that cells are like tiny organisms that can multiply if given the right medium to grow in. It is, for example, skin cells from people very well suited for. By looking closely at cell division has been observed several notable trundle build conditions that have to do with the aging process. Hayflickgrænsen
In 1961, researchers conducted Leonard Hayflick and Moorhead Paul a series of experiments showed that cells grown in the laboratory only can divide a limited number of times. The cells in which it goes into a state in which they do not share more. This limit cell division was called the Hayflick limit.
Hayflick worked with the type of cells, called fibroblasts, which is the body's connective tissue. trundle build Fibroblasts can be extracted from a skin sample are then put in a shallow bowl with a growth medium. The cells will then divide until they cover the entire bowl area in a single layer. If you put some of these new cells into another bowl with growth medium, these cells also multiply until they cover the whole new dish. Hayflick observed that younger human fibroblasts could divide approx. 50 times and no longer.
Hayflick had also observed that while cells from children to share up to 60 times, then, cells from older people only divide about. 20 times. trundle build Based on this observation made Hayflick the hypothesis that this sharing mechanism was fundamental to aging and death.
Hayflicks theories have in recent years been expanded, trundle build inter alia theory telomerforkortelse for each cell division. The cell's genetic material consisting of 23 chromosome pairs containing the genes. The molecular biologists have discovered that chromosome ends are protected by a special structure, called telomeres. When a person fertilization telomeres their maximum length. Each time the cell divides, the telomeres become shorter. The older a person is, the shorter the individual trundle build cell's telomeres. Finally, the telomers are no longer able to protect the chromosomes, and the cell dies. Telomere theory trundle build thus explains why our cells age and eventually will not divide anymore.
The enzyme telomerase can lengthen telomeres, and it might be tempting to imagine that one could prevent cell death by adding the enzyme. Such cells are available, however. Cancer cells contain trundle build telomerase, and is principally characterized by being immortal. So even telomeraseenzymet can prevent cell aging and death, it may not be in the organism of interest.
Telomere theory can not explain why there is so much variation in human life, as we all start life with the same length trundle build telomeres. Therefore, researchers consider other explanatory models must complement trundle build telomere theory. Some researchers argue against the uncritical transfer theories from laboratory petri dishes in which the cells are grown in culture to the entire organism. They have, among other things discovered that cells in certain tissues splits up to 1000 times without problems, and other studies indicate telomerase in tissues in need of cell renewal. Another objection to the telomere theory as an explanation for why we age, is that the telomeres in older people is so long that the basis of telomere theory should have a life expectancy that is 25-50 years of what it is day.
Articles and Themes Biology age in minute detail the aging population, the aging body History Old age in medicine history Aging in mentality story The dream of eternal trundle build life Oldetopia press Releases
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